Vasculitis – Prevention, Diagnosis, and Management

Vasculitis is an inflammation and necrosis of the blood vessels, leading to hemorrhage, ischemia, and infarction.(1–3) Treatment of the condition is entirely dependent on the extent of the disease. In many instances, cutaneous vasculitis is a self-limited condition, relieved by leg elevation, avoidance of standing, and therapy with non-steroidal anti-inflammatory drugs (NSAIDs). However, more extensive…

Classification of Vasculitis

Vasculitis, an inflammation of the blood vessel wall, is associated with multiple cutaneous manifestations as well as systemic sequelae.(1-5) Opinions on the Classification of Vasculitis Opinion is divided over the best way to classify cutaneous vasculitis. Some prefer classification according to etiology, differentiating between primary (idiopathic) and secondary disease.(1) Approximately 50% of cases are idiopathic,…

Sickle Cell Ulcers: Classification and Clinical Features

Sickle cell ulcers are a common characteristic of an uncommon disease. Sickle cell disease predominantly affects black individuals, often having a seriously adverse effect on quality of life. Symptoms associated with sickle cell disease include ‘crisis’ episodes of fever and pain; severe abdominal pain; bone, joint, and back pain; and fertility problems. It has also…

An Introduction to Sickle Cell Ulcers

Let’s look at the relatively uncommon but extremely debilitating issue of sickle cell ulcers. Sickle cell ulcers are a common manifestation of sickle cell disease, which is itself an inherited, genetic disorder of the oxygen-carrying hemoglobin in red blood cells. Sickle Cell Ulcer Statistics Sickle cell disease is particularly common among people whose ancestors come…

Diagnosis of Pyoderma Gangrenosum & Risk Factors

Pyoderma gangrenosum is a rare but serious ulcerating skin disease causing painful ulcers on the legs and other parts of the body. Although pyoderma gangrenosum can affect individuals of any age, it is most common in people in their 40s and 50s. It tends to be associated with inflammatory conditions, including ulcerative colitis, Crohn’s disease,…

Types of Pyoderma Gangrenosum

Pyoderma gangrenosum is a  rare but serious ulcerating skin disease, which can present in many forms and to a variety of health professionals. This means a diagnosis of the condition is often delayed, lead to serious clinical consequences for the patient. [1] Pyoderma gangrenosum presents most commonly on the lower legs, particularly in the pretibial…

A New Topic on WoundTalk – Pyoderma Gangrenosum

The last few weeks on WoundTalk have been devoted to a discussion of lymphedema.  Our new subject for discussion will be pyoderma gangrenosum, an uncommon but potentially incapacitating condition that is still not fully understood. As well as providing a comprehensive overview of this condition, we will also provide resources to assist you in understanding…