Search Results for: wound infection

Diagnosis of Necrotizing Fasciitis & Treatment

Diagnosis of necrotizing fasciitis (NF) can prove extremely challenging. The condition has many of the same characteristics as cellulitis, and is often diagnosed incorrectly as such.(1) The resulting delay in implementing appropriate treatment can prove catastrophic in such a rapidly progressing condition. Cellulitis or Necrotizing Fasciitis? One key differentiator between NF and cellulitis  is the…

Causes of Necrotizing Fasciitis & Risk Factors

Necrotizing fasciitis (NF), or the ‘flesh-eating bug’ as it tends to be known in the press, is an extremely rapidly progressing infection that is difficult to manage and can lead to significant morbidity and mortality. Risk Factors of Necrotizing Fasciitis While anyone with an infection may, in theory, develop NF, in practice the majority of…

Necrotizing Fasciitis – Introduction

Necrotizing fasciitis (NF) is a life-threatening soft tissue infection a condition, often referred to in the press as the ‘flesh-eating bug’ on account of the speed with which the infection spreads.  The condition was first described by Hippocrates around the fifth century, and the term “necrotizing fasciitis” was coined by Joseph Jones, a former Confederate…

Vasculitis – Prevention, Diagnosis, and Management

Vasculitis is an inflammation and necrosis of the blood vessels, leading to hemorrhage, ischemia, and infarction.(1–3) Treatment of the condition is entirely dependent on the extent of the disease. In many instances, cutaneous vasculitis is a self-limited condition, relieved by leg elevation, avoidance of standing, and therapy with non-steroidal anti-inflammatory drugs (NSAIDs). However, more extensive…

Classification of Vasculitis

Vasculitis, an inflammation of the blood vessel wall, is associated with multiple cutaneous manifestations as well as systemic sequelae.(1-5) Opinions on the Classification of Vasculitis Opinion is divided over the best way to classify cutaneous vasculitis. Some prefer classification according to etiology, differentiating between primary (idiopathic) and secondary disease.(1) Approximately 50% of cases are idiopathic,…

An Introduction to Sickle Cell Ulcers

Let’s look at the relatively uncommon but extremely debilitating issue of sickle cell ulcers. Sickle cell ulcers are a common manifestation of sickle cell disease, which is itself an inherited, genetic disorder of the oxygen-carrying hemoglobin in red blood cells. Sickle Cell Ulcer Statistics Sickle cell disease is particularly common among people whose ancestors come…

Management of Biofilms

As discussed over the previous two weeks’ articles, biofilms are communities of microorganisms that attach to the wound surface encasing themselves in an extracellular polysaccharide matrix.1 As biofilms can present a real barrier to wound healing, it is important that they are identified and dealt with as a matter of priority.2 The first step towards managing…

Looking Inside a Biofilm

Biofilms are communities of microorganisms that attach to the wound surface encasing themselves in an extracellular polysaccharide matrix.1 Because multiple types of organism can exist synergistically within a biofilm, often displaying remarkable antibacterial resistance, biofilms can present a real barrier to wound healing.2 Biofilm Formation The complex molecular nature of a biofilm is not yet…