Calciphylaxis – Wrap Up


Another topic covered – and another quiz! In the latest short series of articles we have taken a brief look at the devastating condition known as calciphylaxis. Calciphylaxis is a condition that occurs predominantly in individuals with advanced chronic kidney disease, leading to vascular calcification, thrombosis, and skin necrosis.

Lack of Treatment Options

The pathophysiology of calciphylaxis is complex and poorly understood, and the prognosis for patients is dismal. There is much more work to be done before patients with calciphylaxis can be offered anything approaching a cure. In particular, randomized clinical trials different treatment options for calciphylaxis are urgently required. In the meantime, management consists largely of strategies for prevention, as well as evidence-based wound management techniques.

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